Hepatic Dosing Calculator

Calculate medication dose adjustments for patients with liver disease using Child-Pugh scoring and hepatic extraction considerations.

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Important Health Disclaimer

This calculator provides general health information based on standard medical formulas and WHO guidelines. Results are for informational and educational purposes only and should not be considered as professional medical advice, diagnosis, or treatment recommendations.

For health concerns, medical conditions, fitness plans, or dietary decisions, please consult with qualified healthcare professionals, licensed physicians, registered dietitians, or certified fitness trainers who can evaluate your individual health status and medical history.

Individual health needs vary significantly. These calculations are general estimates and may not be appropriate for everyone, especially those with existing medical conditions, pregnant women, children, or elderly individuals.

Not a substitute for professional medical advice

Child-Pugh Parameters

mg/dL

Normal: <1.2 mg/dL

g/dL

Normal: 3.5-5.0 g/dL

Normal: 0.9-1.1

Drug Information

mg

Child-Pugh Score

6 (Class A)

Well-compensated

πŸ’ŠAdjusted Dose
375 mg
πŸ“‰Dose Reduction
25%
πŸ“ŠAdjustment Factor
75%
πŸ“ˆ1-Year Survival
100%

Score Components

Bilirubin: 1 point(s)

Albumin: 2 point(s)

INR: 1 point(s)

Ascites: 1 point(s)

Encephalopathy: 1 point(s)

Recommendation

Mild impairment - may need minor adjustment for high-extraction drugs

Child-Pugh Classification

ClassScoreSeverityDose Adjustment
A5-6MildUsually none needed
B7-9Moderate50-75% of normal
C10-15Severe25-50% of normal
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