Renal Drug Dosage Calculator
Adjust drug dosages based on kidney function using creatinine clearance and various adjustment methods.
Important Health Disclaimer
This calculator provides general health information based on standard medical formulas and WHO guidelines. Results are for informational and educational purposes only and should not be considered as professional medical advice, diagnosis, or treatment recommendations.
For health concerns, medical conditions, fitness plans, or dietary decisions, please consult with qualified healthcare professionals, licensed physicians, registered dietitians, or certified fitness trainers who can evaluate your individual health status and medical history.
Individual health needs vary significantly. These calculations are general estimates and may not be appropriate for everyone, especially those with existing medical conditions, pregnant women, children, or elderly individuals.
Not a substitute for professional medical advice
Patient Information
Drug Parameters
Standard dose for normal renal function
Creatinine Clearance (CrCl)
48.6 mL/min
Moderate reduction (CKD Stage 3)
Adjustment Options
Dose Reduction: 375 mg every 8 hours
Interval Extension: 500 mg every 10.7 hours
Combined: 433 mg every 9.2 hours
Daily Dose Comparison
Normal daily dose: 1500 mg/day
Adjusted daily dose: 1125 mg/day
Clinical Warning
This is a general guide. Actual dose adjustments vary by drug. Always consult current drug references and consider other patient factors including dialysis status.
CKD Staging & Dosing Guide
| CKD Stage | GFR/CrCl (mL/min) | Description | Typical Adjustment |
|---|---|---|---|
| Stage 1 | ≥90 | Normal function | No adjustment |
| Stage 2 | 60-89 | Mild reduction | No adjustment usually |
| Stage 3a | 45-59 | Mild-moderate reduction | Consider adjustment |
| Stage 3b | 30-44 | Moderate-severe reduction | 25-50% dose reduction |
| Stage 4 | 15-29 | Severe reduction | 50-75% dose reduction |
| Stage 5 | < 15 | Kidney failure/ESRD | 75%+ reduction, consider dialysis |
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